MegaSporeBiotic

MegaSporeBiotic

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$65.99
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A 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria.

MegaSporeBiotic™ does not require refrigeration and maintains a healthy gut microbiome.

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Microbiome Labs is innovating wellness solutions by restoring balance and diversity in the microbiome for whole-body restoration.

  • Science-Driven

    A balance of biological innovation and scientific validation

  • Probiotic Pioneers

    Originators of clinically validated spore-based probiotics

  • Innovative Biotechnology

    Evidence-based solutions that help enhance care across health categories

  • Microbiome Optimization

    Committed to whole health through balance and restoration of the gut

    At a glance

    MegaSporeBiotic is a probiotic blend of 5 Bacillus spores that have been shown to maintain healthy gut barrier and immune function. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract.

    Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims toRECONDITIONthe gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.

    Bacillus Licheniformis

    Produces proteases that aid protein digestion
    Produces full spectrum of B vitamins

    Bacillus indicus HU36

    Produces carotenoids: lycopene, astaxanthin, beta-carotene, and lutein
    Produces quinols and vitamins

    Bacillus Subtilis Hu58"

    Produces nattokinase and vitamin K2
    Supports healthy GALT development

    Bacillus Clausii

    Supports immune function

    Bacillus Coagulans

    Produces L+ optical form of lactic acid
    Supports immune function

    How It Works

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    Recondition

    Spore-based strains survive stomach acid and become active in the gut.

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    Reinforce

    Supports growth of beneficial commensal bacteria, strengthening microbial diversity.

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    Rebuild

    Improves gut barrier integrity and digestive-immune resilience.

    Dosing instructions

    Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.

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      Microbiome Labs was first in the market with spore-based probiotics.
      We continue to lead with 10 peer-reviewed efficacy studies.

      Key Benefits

      • Promotes healthy gut barrier function and intestinal integrity.
      • Enhances microbial diversity and supports commensal gut bacteria populations.
      • Travel-friendly, shelf-stable formula that does not require refrigeration.

      FAQ

      What makes MegaSporeBiotic different from regular probiotics?

      Unlike traditional probiotics that use fragile lactobacillus or bifidobacterium strains, MegaSporeBiotic is 100% spore-based—meaning its beneficial bacteria are naturally protected by a spore shell. This allows them to survive stomach acid and reach the intestines alive.

      Do I need to refrigerate MegaSporeBiotic?

      No. It’s completely shelf-stable. The Bacillus spores remain dormant until they reach the gut, making refrigeration unnecessary.

      When is the best time to take it?

      Take 1–2 capsules daily with food, preferably at the same time each day. Consistency is more important than timing.

      Can I take MegaSporeBiotic with antibiotics?

      Yes, but take them at least 2–3 hours apart to prevent interference. The product can help restore gut diversity during and after antibiotic use.

      Is it safe for children?

      It can be used under the supervision of a healthcare practitioner. Dosing may vary based on age and body weight.

      What if I feel bloated or gassy at first?

      This is a normal “die-off” or adjustment phase as your gut microbiome rebalances. Simply reduce the dose to half a capsule daily, then slowly increase as tolerated.

      How long before I notice results?

      Many users report improvements in digestion, energy, and bloating within 2–4 weeks. Clinical studies show measurable changes in gut barrier and microbiome diversity within 10–12 weeks.

      Can it help with immune health?

      Yes. A balanced gut microbiome plays a key role in supporting immune defense. MegaSporeBiotic’s spore strains help regulate immune response and reduce occasional inflammation.

      Is it vegan or allergen-free?

      Yes. It contains no dairy, gluten, soy, nuts, or GMOs, and is suitable for most dietary preferences.

      Can I take it while pregnant or breastfeeding?

      Always consult your healthcare provider before starting any supplement during pregnancy or nursing.